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Gardasil 9 may be associated with fainting, so patients will be observed for about 15 minutes after a Gardasil 9 injection
Statistical analysis Based on the sample size calculation, with 15 subjects and an estimated response rate of 0.5, we would achieve the 95% confidence interval (CI) of 0.239 to 0.761, using a two-sided exact binomial test with a type I error of 0.05
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