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unc1(vlt10) enhances synuclein and amyloid aggregation Having shown that unc1 regulates polyQ aggregation, we tested whether its function is polyQspecific or if it affects other aggregationprone proteins, such as synuclein and amyloid that aggregate in brains of Parkinson's and Alzheimer's patients, respectively

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Nilsson PM, Boutouyrie P, Laurent S

While the later emphasized a dose-response effect and found no role for follow-up, however, we observed no consistent dose gradient but did find that longer follow-up linked to greater improvement on self-reported symptoms (BDI only)