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McKesey J, Tovar-Garza A, Pandya AG

doi: 10.1200/PO.21.00076

Human colon function ex vivo : dependence on oxygen and sensitivity to antibiotic

In a dose-escalating study involving 15 healthy male subjects receiving three single doses of AOD9604 and placebo as single dosages, a total of twenty-nine adverse events (AEs) were reported by 12 of the subjects

Treatments with DSIP and the DSIP-CBBBP fusion peptide significantly countered this reduction, showcasing their potential as therapeutic agents for modulating hedonistic behavior

A recent review summarizes safety gaps and the regulatory context in the FDA context
