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A 24-author Sikiric-group review covering skin wounds, burns, diabetic ulcers, surgical defects, and the bleeding/thrombosis literature

PLoS ONE 7 , e33277 (2012)

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[DOI] [PubMed] [Google Scholar] 247.Kohl Z., Ben Abdallah N., Vogelgsang J., Tischer L., Deusser J., Amato D., Anderson S., Mller C.P., Riess O., Masliah E., et al

These compounds aim to reduce inflammation, restore tissue homeostasis, and promote tissue regeneration by modulating the environment surrounding senescent cells.130 Unlike senolytics, which focus on cell death, senomorphics maintain the senescent cells presence but modify its behavior, particularly the pro-inflammatory and tissue-damaging components of the SASP.129 By reducing the detrimental effects of senescent cells, such as the SASP, senomorphics hold promise for treating a range of diseases, including cancer, neurodegenerative disorders, cardiovascular diseases, and metabolic syndromes.26 At the molecular level, senomorphics exert their effects primarily by modulating the signaling pathways that govern SASP production without inducing apoptosis in senescent cells

This is exactly why you need sublingual B12 or, in more serious cases, B12 injections or IV support