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doi:10.1097/JCP.0b013e31829a83f5 15

A randomized trial found that creatine supplementation combined with resistance training produced significantly greater improvements in lean mass, strength, and functional capacity in postmenopausal women compared to resistance training alone [23]

It is postulated that clinical symptoms, including CNS complications such as convulsion, coma and lethargy, may be triggered by the accumulation of metabolites and their acyl-CoA derivatives that disrupt intermediary metabolism [6669]

doi: 10.2165/00044011-200828080-00004
The market has benefited from a substantial patient pool leveraging the ingredient as a dietary supplement in enhancing brain functioning and reducing mental fatigue

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