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found no association between A1298C polymorphism and MTX toxicity [44]

doi: 10.1186/s12876-019-1000-6 66 FleseriuMLangloisFLimDSTVarlamovEVMelmedS
Successful short-term and long-term treatment of melasma and postinflammatory hyperpigmentation using vitamin C with a full-face iontophoresis mask and a mandelic/malic acid skin care regimen
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1 glutathione (GSH) and S-acetyl glutathione (SAG) structures FIG

This can lead to dose-dependent adverse events and confounded experimental data if dosing intervals are not adjusted to account for reduced clearance capacity

The presence of aquaporin-2 channels in the renal collecting ducts cell membranes is necessary for water reabsorption
