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B: However, in the endothelial cells with high level of phosphor AKT, following the block of VEGF stimulation, the AKT pathway remains active inducing transcription of FGF, an angiogenic factor, which on one side promotes endothelium proliferation and on the other further phosphorylates AKT producing a positive loop
Garvey WT, Ryan DH, Look M, Gadde KM, Allison DB, Peterson CA, et al
Varma, P
22 GuptaV.CarrollK
New York, McGraw-Hill Book Company
But, the schedule might change based on how well the treatment works and the cause of the deficiency
