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In addition to its role in lipid metabolism, LC is implicated in amino acid metabolism, namely the transamination of branched-chain amino acids (BCAAs) such as leucine, isoleucine, and valine

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Notwithstanding this infamous ranking, the website also proclaims that "medical advances and prevention efforts have helped Americans fight back against CVD." Then comes the caveat: "Sadly, this remarkable progress has stalled." Apparently this stalled progress refers to the fact that the accepted procedure for treatment---managing cholesterol levels with statin drugs---has failed to rein in skyrocketing CVD rates