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Description
Revised: June/2026 PRINCIPAL DISPLAY PANEL 0.25 mg or 0.5 mg doses, 2 mg/3mL Pen 0.25 mg 0.5 mg NDC 0169-4181-13List 418113 OZEMPIC (semaglutide) injection For Single Patient Use Only 2 mg/3 mL (0.68 mg/mL) Prefilled pen Pen delivers doses in 0.25 mg or 0.5 mg increments only For subcutaneous use only Use OZEMPIC once weekly Contains: 1 OZEMPIC pen, 6 NovoFine Plus 32G needles, Product Literature

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GLP-1R agonists (e.g., exendin-4 and liraglutide) reduce APP expression and processing in the brains of AD model mice through the activation of GLP-1R, decrease A protein production and plaque aggregation, and thus improve their spatial memory capacity (McClean et al., 2015

Additionally, tirzepatide reduced HF symptom severity, improved exercise tolerance, lowered blood pressure, decreased circulatory volume expansion, reduced inflammation, and improved kidney function 3740

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