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The larger bacterium provides a natural protective coating for subtilisin in the stomach, and the enzyme retains its ability to access and degrade the gluten-derived peptides in this form

Quinlan PT, Lane J, Moore KL, Aspen J, Rycroft JA, OBrien DC (2000) The acute physiological and mood effects of tea and coffee

Rarely, metformin may cause potentially serious lactic acidosis, a buildup of lactic acid in the blood (Diabetes.co.uk 2016)

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Bel S, Pendse M, Wang Y et al (2017) Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine