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This offers the rationale to combine TGF inhibitors with anti-VEGF agents (192)

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doi: 10.1097/NEN.0b013e3181a9d503

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the single chain pro-polypeptide is proteoiytically processed by convertases to yield a mature a (heavy chain 55 KDa), and HGF light chain 34 KDa heterodimer, which are bound together by a disulfide link

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