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doi: 10.1016/J.CELL.2024.08.021 14

This feedback loop actually encourages more frequent changing which is a good thing

Nevertheless, the treatment was seen as well tolerated, despite one of the 11 participants dropping out of the study due to stomach pain [61]

10.1248/bpb.b15-00048 Biol

These tests are Standardised Mini-Mental State Examination (SMMSE), 26 attention and processing speed (Trail Making Test-A [TMT-A], executive functions (TMT-B and Stroop Color Word Test), 59 working memory (Digit Span subtest from Wechsler Adult Intelligence Scale-IV [WAIS-IV]) 60 and spatial span subtest Wechsler Memory Scale-III [WMS-III]), 28 visuo-spatial functions (Clock Drawing Test, CDT)

The drivers are not contradictory data they are: substrate concentration (lab tests use 100-1000 mg/L