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This is one reason head-to-head binding assays dont always match head-to-head secretion experiments and why researchers occasionally get surprised when GHRP-6 outperforms GHRP-2 in certain model contexts despite lower receptor binding affinity on paper

J Exp Med 1999

Y-BOCS = YaleBrown Obsessive Compulsive Scale

Cell Death Differ 5:911919
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