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In lupus, SOCS1 function is often impaired, contributing to the uncontrolled immune activation that characterizes the disease
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Furthermore, effector genes GZMB , GNLY , GZMA , PRF1 , IL-2 , IFN as well as the master regulator of exhaustion TOX were significantly downregulated in rapamycin-treated CAR T products (Fig
He also served as the Appointed Advisor for Natural Products to the government of Australia
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