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For example, a translational study showed that ALDH2 suppression was protected by physiologically relevant levels of omega-3 polyunsaturated fatty acids [103, 211], and in a recent phase II clinical trial, treatment with clomethiazole (CMZ), an inhibitor of CYP2E1, mitigated the biomarkers of alcohol-induced oxidative stress and ALD progression [212]

Stem cells and other expandable, self-renewing cell sourceswhether allogeneic or autologousare promising to address these needs

Food Research International, 116, 103-111

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Hemodynamic changes induced by PH and pro-inflammatory cytokines are also known to cause alteration of redox potential affecting the stress-activated signaling cascades

Results Protection from oxidative damage and environmental stress