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Collectively, theyre known as the Virchow triad: a change in blood flow, a blood vessel injury, or a change in the composition of the blood

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These hydroperoxides degrade into reactive aldehydes such as MDA and 4-HNE, which covalently bind to proteins and DNA, disrupting cellular functions (Figure 3) [157,158,159]

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Neuroscience and Behavioral Physiology, 23 (5), 480-485
