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This is a mechanistic reason secretagogues are conceptually distinct from simply adding more hormone, and it is central to why they were studied as potentially gentler tools a hypothesis that, as later sections show, did not automatically translate into a favorable clinical benefit-risk balance

He S, Segura Abarrategi J, Bediaga H, Arrasate S, Gonzlez-Daz H

The delayed gastric emptying is therapeutically beneficial for appetite suppression and glucose control but can cause gastrointestinal symptoms, especially when eating large meals or difficult-to-digest foods

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Effects of Lutein on Brain Damage and Vasospasm in an Experimental Subarachnoid Hemorrhage Model