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Mice from all 4 groups were included

In HFD-induced obese insulin-resistant rats subjected to cardiac ischemiareperfusion injury, dapagliflozin, an SGLT2 inhibitor, exhibited superior cardioprotective efficacy compared with vildagliptin, a DPP-4 inhibitor, as evidenced by suppression of mitochondrial Drp1 expression, reduced infarct size, and improved left ventricular function [199]

Improvement in cognitive abilities was observed after use of tramadol [13], inositol stabilized arginine [19] and polyphenols [17]

[PMC free article: PMC3501207] [PubMed: 23042816] 165

Preclinical FOXO4-DRI treatment reverses cognitive decline and neuropathology

Effect of PEITC on cancer cell energetics and metabolism Cancer cells have a high demand of ATP, which is fulfilled by higher glycolysis rates, a phenomenon known as Warburgs effect