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There are a few different cancers (melanoma, BCC and SCC), and many of these different tumour types look different from each other

Importantly, it should be highlighted that in cases presenting anti-CRP antibodies, false-negative test results may be evident in case samples with poor washing, which can lead to immunocomplexes between CRP and anti-CRP antibodies, thus lowering free CRP levels in the final analyzed sample, and apart from such immunocomplexes, it was also discussed that CRP can bind to soluble receptors or exist in plasma microvehicles

Viale et al., 2015)

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As indicated above, the free cholesterol is either incorporated into plasma membranes or esterified (by SOAT2