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Certain cancers, like those driven by Myc, rely on glutamine, making targeting glutamine metabolism pharmacologically beneficial
A.AslamS.GuptaR.et al
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This purification procedure involved an initial affinity chromatography step (anti-FLAG column or IMAC, immobilized metal ion affinity chromatography, depending on GPX4 tag) followed by a second size exclusion chromatography step (GE)

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Leitsch, D