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2.3 Fatigue score measurement During the clinical visits, the treating physician recorded the fatigue level using Question 1 adapted from the Bristol rheumatoid arthritis fatigue numerical rating scale (BRAF-NRS) (37)

Effects of acetyl-L-carnitine and methylcobalamin for diabetic peripheral neuropathy: A multicenter, randomized, double-blind, controlled trial
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Ovidius University Annals, Physical Education and Sport/Science, Movement and Health Series 2010;10(Suppl 2):504-507

These processes involve the activation of muscarinic cholinergic receptors in the forebrain, and an increased expression of type-2 metabotropic glutamate (mGlu2) receptors in dorsal root ganglia neurons

10.1038/nm.3145 [DOI] [PubMed] [Google Scholar] 77

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