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For a weekly injection schedule, you'll be repeatedly piercing the stopper and drawing from the same vial over 4+ weeks

Why rebound happens Metabolic adaptation Long-term weight maintenance is difficult partly because energy expenditure often drops more than expected after weight loss, a phenomenon known as adaptive thermogenesis, and that reduced expenditure can persist while weight is suppressed

[DOI] [PubMed] [Google Scholar] 53.Matheny M, Strehler KY, King M, Tumer N, Scarpace PJ