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The study showed mechanistically that mtDNA released into the cytosol can bind to NLRP3, triggering its activation and the subsequent production of inflammatory cytokines like IL-1, contributing to inflammation in lung tissues (Nakahira et al., 2015) (Figure 2)
Dorso-Lateral prefrontal cortex
Journal of Psychosomatic Research , vol
[DOI] [PMC free article] [PubMed] [Google Scholar] [6].Drake J, Link CD, Butterfield DA
[DOI] [PubMed] [Google Scholar] Gunnarsdottir S and Elfarra AA
The p70S6K1 phosphorylation was induced in all cells treated with BMS-754807 for 4872 h (Fig
