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Neuroscience, 156 (3), 693699

BioFactors 8(12):9396 Cederbaum AI (2006) Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells

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Comparing with wild genotype (CC), the heterozygote (CT) and mutation homozygote (TT) lead to the decline of enzyme activity by about 34 and 75%, and increased thermolability in lymphocyte extracts 25