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Nature 500 , 404405 (2013)

Extinction coefficients of HT adducts were measured in the presence of a twofold excess of HT protein to ensure quantitative reaction of the ligand

A 4:1 carb to protein ratio with a complete amino acid profile

At 2mg five times weekly, 100mg lasts about 10 weeks, covering most protocols

Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
