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Individuals with known hypersensitivity to ascorbic acid, those with a history of oxalate kidney stones, G6PD deficiency, iron overload disorders, or severe renal impairment should avoid this product
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Gerli, et al., 1990

Kasi PM, Dayyani F, Morris VK, Kopetz S , Parikh AR, Starr JS, Cohen S, Grothey A, Lieu CH, O'Hara MH, Loranger K, Westbrook L, Sharma S, Krinshpun S, Hook N, Zimmermann B, Billings PR, Aleshin A

The effects are concentration-dependent in ways that arent always linear, so skipping dose-response curves in your model is asking for trouble
