glutathione s transferase detoxification transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases The Multifaceted Role of Glutathione

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HepG2 cells exhibited higher catalase activity than HeLa cells, and inhibiting catalase activity by using 3-aminotriazole (3-AT, a specific inhibition of catalase) or catalase siRNA remarkably reduced the resistance of HepG2 cells to ROS, demonstrating the key roles of catalase for the strong resistance of HepG2 cells to ROS