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Increase of fat oxidation and weight loss in obese mice by a fragment of human growth hormone

Fatigue or headaches Rare but can occur in individuals sensitive to peptides affecting metabolic pathways

This is common with many metabolic peptides and supplementsyour body develops tolerance, and the initial benefits diminish

Hence the need for loading doses

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J Clin Invest 89 : 19081913 Ethics declarations Competing interests The authors declare no competing financial interests