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But ferritin had a J-shaped link to DKD (Gong et al., 2025)
The second mechanism involves the nuclear transcription factor NRF2 (nuclear factor erythroid 2-related factor 2), which governs the cell's antioxidant defense network
B., Chonchol, M., & Seals, D
M., Pierce, A
This is about cellular health, not just lab results
In addition, CRISPR-Cas9 gene editing enables precise modification of PF-related genes such as desmoplakin (DSP) and CD5 molecule-like (CD5L), presenting new strategies to reduce genetic risk and develop targeted therapies (Qu et al., 2018
