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M1 macrophages produce high levels of proinflammatory cytokines and upregulate the expression of the surface markers CD80 and CD86 [61], whereas M2 macrophages express anti-inflammatory markers and mediators, including the mannose receptors CD206 and CD163 [62]

6.4 Addressing global and socioeconomic gaps Most PD research and trials are concentrated in high-income countries, neglecting ethnic diversity, LMIC-specific risk factors, and accessibility challenges

[PMC free article: PMC3047226] [PubMed: 21193540] 19

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doi: 10.1016/j.ecoenv.2012.02.028 14

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis