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In addition to the DAergic neurodegeneration model, we also tested the effect of HLEA-P1 on the -synucleinopathies using the transgenic C

Enteroviral 2B protein has been shown to interact with mitochondrial voltage-dependent anion channel 3 (VDAC3) to induce ROS production, and knockdown of VDAC3 significantly reduces EV71-induced mtROS generation and viral replication 132

Glutathione helps regulate this response by modulating the activity of immune cells and cytokines

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10.1007/s10803-011-1260-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 60.Hanson E, Kalish LA, Bunce E, Curtis C, McDaniel S, Ware J, et al