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Narayanaswami P, Sanders DB, Wolfe G, et al

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For example, it has been found that polydatin promotes mitochondrial biogenesis and protects against mitochondrial oxidative stress via the activation of Sirtuin-1-PGC-1 pathway and Sirtuin-1-Nrf2-ARE pathway in kidney diseases (Huang et al., 2015

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On the contrary, the elevated baseline levels of cell death appear to impair the ability of ADA2-deficient cells to undergo necroptosis (Figs

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