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They also profoundly influence the behavior of other cells within the joint, particularly the activation state of immune cells like FLS and infiltrating macrophages, by modulating signals such as lipid peroxidation products and debris released from dying cells

PMID 8692483

*Correspondence: Hongjun Li, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

& Correa-Rocha, R

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Vessels isolated from diabetic subjects exhibit increased superoxide production that is inhibited by diphenylene iodinium, and demonstrate increased expression of several NAD(P)H oxidase subunits (p22phox, p47phox, and p67phox) [17], suggesting that NAD(P)H oxidases are more active in diabetes