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397,398 The KAITLIN phase 3 study compared anthracycline-based chemotherapy and then 18 cycles of T-DM1 plus pertuzumab (AC-KP) to taxane (threefour cycles) plus trastuzumab plus pertuzumab (AC-THP), adjuvant AC-KP did not result in statistically significant or clinically meaningful improvement in iDFS compared with AC-THP in patients with high-risk early breast cancer

References 1.Bolli R, Jeroudi MO, Patel BS, DuBose CM, Lai EK, Roberts R, et al

Yang G, Xia Y, Ren W

1 , eaai7793 (2016)

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