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People have reported everything from a sore, red tongue (glossitis) and ringing in the ears (tinnitus) to feeling an internal buzzing sensation or even experiencing visual disturbances

(2004) Insulin-like growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes

The essential amino acid tryptophan also depends on B6 for its utilization

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No evidence of genotoxic activity was found in either assay
