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Notably, L2HG-induced ferroptosis occurs independently of impaired cystine uptake, transsulfuration pathway activity, or increased GPX4-mediated GSH utilization, revealing a non-canonical ferroptosis mechanism driven by enhanced GSH catabolism

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Supplement marketers really feel like we're going to open the paper or turn on the radio one day and find out our products are non-compliant, says Jeff Cohen, co-founder of the American Peptide Association.