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By the time patients reach the maintenance dose of 2.4mg for weight management, GI symptoms are at their peak frequency

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ACE2 Expression in the GI Tract The gastrointestinal system serves as a key target for SARS-CoV-2 due to its robust expression of angiotensin-converting enzyme 2 (ACE2) receptors

The loading phase is extended, with injections given on alternate days until no further improvement is observed, which may take several weeks or months

Therefore, while the quick benefits can be appealing, they should not be the sole consideration when evaluating the effectiveness of these injections

My neck would feel ON FIRE, then within minutes if I didnt grab an ice pack, I was knee-deep in a migraine