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Romero-Figueroa MDS, Ramrez-Durn N, Montiel-Jarqun AJ, Horta-Baas G
On the other hand, Fe 2+ and Fe 3+ are also cofactors that can enhance the activities of various metabolic enzymes, resulting in the formation of free radicals such as alkoxy (RO) and peroxy (RO 2 ), promoting lipid peroxidation, and inducing ferroptosis ( 1 ) and iron regulatory protein 2 (IRP 2 ) regulate intracellular iron storage, release, entry, and exit, thereby maintaining cellular iron homeostasis

Affected sites of chemotherapy toxicity in the peripheral nervous system are shown in Fig

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Pb impairs both GABA uptake and depolarization-evoked release in synaptosome preparations, likely through reduced expression of glutamate decarboxylase (GAD) and compensatory upregulation of GABA transporter 1 (GAT-1) [47,48,71]

Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
