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Cholestyramine, a bile salt resin, effectively alleviates cholestatic pruritus and is the first-line treatment even in cirrhosis due to its general tolerability and safety (4)

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Mongioi L, Calogero AE, Vicari E, Condorelli RA, Russo GI, Privitera S, et al

L-Carnitine is studied for its role in transporting long-chain fatty acids into mitochondria, where they can be evaluated in energy metabolism and fatty acid oxidation research models

It has been found that the mitochondrial glutaminase 2 (GLS2), and not the cytosolic GLS1, appears to be involved in ferroptosis [232, 233]

Mitochondrial formation of reactive oxygen species

this method suffers from a disadvantage associated with a difficulty of application thereof to a practical process due to a high cost of (S)-3-hydroxy-gamma-butyrolactone as the starting material