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Discussion The role of L-carnitine in weight reduction in humans and mouse models has been reported in a number of studies

The mechanisms of these agents vary greatly, and include the manipulation of gut microbial composition, reduction of oxidative stress, inhibition of inflammatory mediators, protection of endothelial integrity, modulation of neurotransmitter release and function, and other novel methods to reduce blood ammonia and neurotoxins

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All of the mutations shown in Figure 6B were found in exons 3 and 6 or 10 and 11, which are located in the N-terminal and C-terminal domains, respectively (Figure 6A)

Duan Y, Li F, Tan K, Liu H, Li Y, Liu Y, et al