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As a result, daratumumab has shown a remarkable impact in treating lupus patients ( Mayo Clinic is currently conducting a Phase 2 clinical trial (NCT04868838) to assess the effectiveness and safety of Daratumumab in patients diagnosed with active LN

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31 Phenformin has been reported to exhibit anti-thiamine activity in animals, 3234 and as a result, it has been suggested that a possible anti-thiamine effect of metformin might contribute to some cases of metformin-associated lactic acidosis, a rare condition, but one that has been shown to have a mortality rate of 1825%