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In regard to the reaction with thiols, experiments with either low-molecular-weight (LMW) persulfides (Artaud and Galardon, 2014

Noteworthy, curcumin both upregulates/down-regulates TGF- signaling pathway in diseases therapy

In practice, this stabilization can cause some users to feel emotionally flat, experience less pleasure from daily activities, or feel a lack of strong emotions, especially when taken in high doses or over a long period

267 , 268 , 269 According to WHO, Social determinants of health are the nonmedical factors that influence health outcomes

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Peer review Peer review information Nature Communications thanks Chuang-Chuang Li and the other anonymous reviewer(s) for their contribution to the peer review of this work