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Although NETs have been proposed to comprise a unique method of microbial killing [182,183], they have also been implicated in tissue damage and organ failure [184,185]

erinaceus has shown beneficial effects in a number of clinical conditions, besides IBD, due to its anti-inflammatory and anti-tumorigenic effect

IVIG mediates its immunomodulatory action by suppressing autoantibody activity, modulating cytokine networks, inhibiting complement activation, and regulating Fc receptor expression on immune cells [100,101,102]

10.1242/jcs.106682 135 NakajimaE

Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity

Preexisting heterogeneity of inducible nitric oxide synthase expression drives differential growth of Mycobacterium tuberculosis in macrophages