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The role of link-protein in the structure of cartilage proteoglycan aggregates

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Nernst and Brunner incorporated Ficks first law of diffusion and modified the Noyes-Whitneys equation to: where, D = diffusion coefficient ( diffusivity ) of the drug A= surface area of the dissolving solid Kw/o = water/oil partition coefficient of the drug considering the fact that dissolution body fluids are aqueous

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