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Jagadeesan et al., 2023)

Unlike full-length erythropoietin, ARA-290: Does not bind the classical erythropoietin receptor responsible for red blood cell production Does not increase hematocrit Does not stimulate bone marrow erythropoiesis Instead, it selectively activates anti-inflammatory and cytoprotective pathways

When stored properly in BAC water, a reconstituted peptide is typically stable and effective for at least 4-6 weeks

Mol Cancer 21:144

doi: 10.1016/j.coph.2022.102345 12 ZhouZHultgrenKE

The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy