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doi: 10.1016/j.clnu.2010.04.002 257 IkedaYMatsudaS

2.2 SLC7A11 and the mechanism of glioma development Ferroptosis is an important form of programmed cell death that occurs in gliomas, the intracellular antioxidant system often fails to eliminate excessive ROS generated by iron ion-induced Fenton reactions and lipid peroxidation
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Researchers often integrate glutathione ratios with NADPH/NADP balance, ROS markers, or antioxidant enzyme activity to build a more robust redox profile

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