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2022;34(3):396-407.e6

They are not FDA-approved drugs, but they are widely used in research and experimental settings to enhance understanding of healing mechanisms

One reason could be that in vivo-studies are much more expensive and sophisticated

The difference between 5 units and 7 units on a syringe is tiny, and that small measurement error could mean a 40% dosing difference

Brattstrm L, Lindgren A, Israelsson B, Andersson A, and Hultberg B (1994)

It has shown non-inferiority to monthly ranibizumab in visual outcomes
