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Meta-analysis of randomized controlled trials shows L-carnitine supplementation significantly reduces CRP (weighted mean difference -1.23 mg/L), IL-6 (-0.85 pg/dL), and TNF- (-0.37 pg/dL), with greater effects observed in studies exceeding 12 weeks duration.[4] In obese patients, L-carnitine combined with synbiotics reduced IL-6 by 34%, hs-CRP by 10%, TNF- by 19%, and malondialdehyde by 22%.[5] L-carnitine also improves inflammatory markers in chronic kidney disease, cardiovascular disease, and metabolic conditions.[6] Acetyl-L-carnitine offers distinct advantages for neuroinflammation through multiple mechanisms beyond simple carnitine delivery

Point Prevalence Survey of Healthcare-Associated Infections and Antimicrobial Use in European Acute Care Hospitals 20022023 (ECDC, 2024)

Specification: Appearance: White crystalline powder

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[DOI] [PubMed] [Google Scholar] Tyni T, Kivela T, Lappi M, Summanen P, Nikoskelainen E, Pihko H