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Kidney function should be adequate, as carnitine metabolism relies on renal clearance

(2002) Effects of oral L-carnitine supplementation on in vivo long-chain fatty acid oxidation in healthy adults

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In an animal model of liver injury, carnitine blocked the essential pathways involved in nitric oxide synthase activity by inhibiting the nuclear factor-kappa B (NF- B) and phosphatidylinositol 3-kinase/Akt pathways