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Loggia studied painful conditions with evidence of neuroinflammation using PET to tag TSPO

10.1016/S0887-8994(97)00026-X Warter JM, Imler M, Marescaux C, Chabrier G, Rumbach L, Micheletti G, Krieger J: Sodium valproate-induced hyperammonemia in the rat: role of the kidney

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Smith R.L., Soeters M.R., Wst R.C.I., Houtkooper R.H

Tryptophan was found to reduce wakefulness after sleep onset and increase sleep efficiency as measured with actigraphy in all participants and improve subjective sleep quality scores in those carrying the genetic variant of interest